DIMENSION

Sage Therapeutics.

The DIMENSION study offered by Sage Therapeutics, Inc. is investigating SAGE-718 for the treatment of cognitive symptoms associated with Huntington disease (HD) in adults with premanifest or early manifest HD. SAGE-718 has been granted Fast Track Designation by the United States Food and Drug Administration (FDA) in September 2021 as a potential treatment for HD. Fast Track is a process designed to facilitate the development and review of new treatments for serious conditions with unmet medical need, such as HD.

DIMENSION is a Phase 2, randomized, double-blind, placebo-controlled study. The objectives of DIMENSION are to:

• Evaluate the efficacy of SAGE-718 to reduce cognitive symptoms associated with HD
• Evaluate the safety and tolerability of SAGE-718 in subjects with HD

The study is registered at ClinicalTrials.gov.

Status
Currently recruiting.

Study Type
Phase II Clinical Trial

Canadian Locations:

Ontario

Location: Sage Investigational Site
North York, ON  M2K 1E1
Status: Recruiting

Nova Scotia

Location: Sage Investigational Site
Halifax, NS B3S 1N2
Status: Recruiting

Quebec

Location: Sage Investigational Site
Montréal, QC H2X 0A9
Status: Recruiting

Source 

ClinicalTrials.gov

For more detailed information on this study and others and for the most recent updates, please go to clinicaltrials.gov. ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world.